1 Scope of Application

Pharmaceutical nitrogen machine is mainly used in drug production, storage, packaging, packaging and other fields.

Usually easy to oxidize water needles (penicillin, etc.) and large infusion (such as amino acids, etc.) need to be protected by nitrogen flushing, otherwise the liquid is easy to oxidize in the storage period, that is, metamorphism. Generally, before packaging, the way of front-flush nitrogen and then flush nitrogen (or a single flush nitrogen) is used, so that the oxygen concentration in the ampoule or infusion bottle is reduced to below 0.5%, and the liquid can be preserved for a long time. At present, the equipment purchased by the general manufacturer is about 5-20 m3/h, and the purity is 99.99%. The difference between pharmaceutical nitrogen machine and other nitrogen equipment is that due to the international standard GMP standard of the pharmaceutical industry, the parts in contact with drugs or pharmaceutical liquid are made of stainless steel and the requirements of sterilization, the equipment needs to be made of stainless steel, and the equipment nitrogen outlet is equipped with a sterilization filter device. Because of the overall high requirements for equipment, pharmaceutical companies usually have high-end configurations.

There are other raw material manufacturing plants, which also need nitrogen protection, and its nitrogen process is more like the nitrogen method of fine chemical plants. Usually the purity is 99-99.9%, but depending on the size of the factory and the amount of difference, but relative to the amount of medicinal nitrogen machine is much larger.

2 Working Principle

Nitrogen making machine is based on air as raw material, high-quality carbon molecular sieve as adsorbent, the use of pressure swing adsorption principle (PSA), the use of molecular sieve filled with micropores, selective adsorption of air, in order to achieve the purpose of oxygen and nitrogen separation. Oxygen is preferentially adsorbed and nitrogen is obtained from non-adsorbed phase when the molecular sieve is pressurized. In this way, enriched components of nitrogen can be obtained in the gas phase. Therefore, by using the characteristics of carbon molecular sieve for oxygen and nitrogen adsorption difference in a certain time, the automatic control software carries out pressure adsorption according to a specific time program, and the cyclic process of atmospheric pressure analysis to complete the separation of oxygen and nitrogen, so as to obtain the finished nitrogen with high purity.

jpg" style="width: 500px; height: 364px;"  />

3 Performance Characteristics

1. Process characteristics:

(1) The pressure swing adsorption nitrogen production equipment has the characteristics of wide applicable air source, high product purity, simple process, high degree of operation automation, low operating costs, etc.

(2) The compressed air purification component has a long service life and is easy to replace and maintain.

(3) The outlet flow of nitrogen production equipment is large, and the outlet pressure can be adjusted within the set range.

(4) It can be opened and stopped at any time according to the production situation.

(5) The product has high nitrogen purity, and the nitrogen purity can be reached >99.99% by pressure swing adsorption, and there is no need to configure nitrogen purification equipment.



2. Technical design features:

(1) The unique molecular sieve compaction technology and pressing device are adopted, which not only avoids the phenomenon of molecular sieve pulverization caused by the impact of air flow on the molecular sieve in the high-speed flow, but also improves the reliability of long-term operation of the system.

(2) Scientific and reasonable process flow and equipment configuration, equipment compact structure, beautiful appearance, small footprint.

(3) The equipment has low operating cost, stable and reliable nitrogen purity and flow.

(4) Air pretreatment part of the equipment, each stage of the filter has a differential pressure indication, automatic blowdown system.

(5) The equipment uses standard parts to connect and disassemble, making installation and maintenance more convenient and convenient.

(6) With high reliability imported program control valve, long service life, can meet the needs of long-term stable operation of equipment.

(7) High degree of automation, using the microcomputer automatic program control system developed by our company, the equipment can be automatically operated, and the purity, pressure and flow of nitrogen can be adjusted according to needs.